Source: Narcolepsy and influenza A (H1N1) pandemic 2009 vaccination in the United States external icon The study found that vaccination with influenza vaccines containing the 2009 H1N1 virus strain used in the United States was not associated with an increased risk for narcolepsy. The analysis included more than 650,000 people who received the 2009 pandemic flu vaccine and over 870,000 people who received the 2010-2011 seasonal flu vaccine. In 2014, CDC published a study to assess the occurrence of narcolepsy following vaccination with 2009 H1N1 influenza vaccine or 2010-2011 seasonal influenza vaccine, both of which contained the 2009 H1N1 virus strain (more about types of influenza viruses). Vaccine Adverse Event Reporting System (VAERS) and the Vaccine Safety Datalink (VSD) and found no indication of any association between U.S.-licensed H1N1 or seasonal influenza vaccine and narcolepsy. In response to the events in Europe, CDC reviewed data from the U.S. Pandemrix was not licensed for use in the United States. Adjuvants are substances added to a vaccine to increase the body’s immune response to that vaccine. It contains an oil-in-water emulsion adjuvant called ASO3. It was not used before 2009, and has not been used since the influenza pandemic season (2009-2010). Pandemrix is manufactured by GlaxoSmithKline in Europe and was specifically produced for pandemic 2009 H1N1 influenza. About narcolepsy and other sleep disorders. This disorder is caused by the brain’s inability to regulate sleep-wake cycles normally, but it can be treated with medication and behavior modification. Narcolepsy is a central nervous system disorder characterized by excessive daytime sleepiness (EDS) and abnormal manifestations of rapid eye movement (REM) sleep. This risk was initially found in Finland, and then other European countries also detected an association. An increased risk of narcolepsy was found following vaccination with Pandemrix, a monovalent 2009 H1N1 influenza vaccine that was used in several European countries during the H1N1 influenza pandemic.
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